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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-KKL-35
KKL-35

Chemical Structure : KKL-35

CAS No.: 865285-29-6

KKL-35 (KKL 35, KKL35)

货号: PC-70354Not For Human Use, Lab Use Only.

KKL-35 is a small molecule inhibitor of trans-translation that has broad-spectrum antibiotic activity, inhibits the trans-translation tagging reaction with an IC50 of 0.9 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

KKL-35 is a small molecule inhibitor of trans-translation that has broad-spectrum antibiotic activity, inhibits the trans-translation tagging reaction with an IC50 of 0.9 uM.
KKL-35 exhibits broad-spectrum antibiotic activity, validating trans-translation as a target for drug development.
KKL-35 prevented growth of B. anthracis and M. smegmatis with MIC values ≤6 µM (<2 µg/mL).

物理化学性质&存储条件

分子量 317.7
分子式 C15H9ClFN3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-chloro-N-(1-propyl-1H-tetrazol-5-yl)benzamide

参考文献

1. Ramadoss NS, et al. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10282-7.

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