KKL-10 |CAS:952849-76-2 Probechem Biochemicals

Chemical Structure : KKL-10

CAS No.: 952849-76-2

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KKL-10 (KKL10)

货号: PC-61265Not For Human Use, Lab Use Only.

KKL-10 is a small-molecule inhibitor of bacterial ribosome rescue that exhibits broad-spectrum antimicrobial activity against bacteria grown in liquid culture.

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5 mg	￥1580	In stock
25 mg	￥3580	In stock
100 mg	￥6480	In stock
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生物&药学活性

KKL-10 is a small-molecule inhibitor of bacterial ribosome rescue that exhibits broad-spectrum antimicrobial activity against bacteria grown in liquid culture; exhibits exceptional antimicrobial activity against both attenuated (LVS) and fully virulent strains of F. tularensis (Schu S4) in vitro with MIC of 0.12 and 0.48 ug/mL, respectively; arrests intracellular growth of F. tularensis during all stages of infection, does not affect macrophage viability or function.

物理化学性质&存储条件

分子量	364.217
分子式	4H10BrN3O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-Bromo-N-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]-2-thiophenecarboxamide

参考文献

1. Goralski TD, et al. Antimicrob Agents Chemother. 2016 May 23;60(6):3276-82.

KKL-10 (KKL10)

生物&药学活性

物理化学性质&存储条件

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KKL-10 (KKL10)

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