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首页-小分子抑制剂&激动剂-Tyrosine Kinase-c-Kit-KIT inhibitor 7
KIT inhibitor 7

Chemical Structure : KIT inhibitor 7

CAS No.: 3080682-21-6

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KIT inhibitor 7

货号: PC-27377Not For Human Use, Lab Use Only.

KIT inhibitor 7 is a potent, highly selective, orally bioavailable KIT inhibitor with IC50 of 2.8 nM, exhibits excellent broad kinome selectivity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

KIT inhibitor 7 is a potent, highly selective, orally bioavailable KIT inhibitor with IC50 of 2.8 nM, exhibits excellent broad kinome selectivity.

物理化学性质&存储条件

分子量 394.39
分子式 C20H16F2N6O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(5-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-4-fluoro-2-methylphenyl)-6-fluoropyrazolo[1,5-a]pyridine-3-carboxamide

参考文献

1. Chen KY, et al. J Med Chem. 2026 Jul 26. doi: 10.1021/acs.jmedchem.6c00898.

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