KIN1400 | IRF3 agonist, RLR agonist | Probechem Biochemicals

Chemical Structure : KIN1400

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KIN1400 (KIN-1400, KIN 1400)

货号: PC-70050Not For Human Use, Lab Use Only.

KIN1400 (KIN-1400) is a potent RIG-I-like receptor (RLR) agonist that triggers IRF3-dependent innate immune antiviral genes and IFN-β expression.

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生物&药学活性

KIN1400 (KIN-1400) is a potent RIG-I-like receptor (RLR) agonist that triggers IRF3-dependent innate immune antiviral genes and IFN-β expression.
KIN1400 shows antiviral activity against a broad range of RNA viruses, including dengue virus, and hepatitis C virus, as well as viruses of the families Filoviridae (Ebola virus), Orthomyxoviridae (influenza A virus), Arenaviridae (Lassa virus), and Paramyxoviridae (respiratory syncytial virus, Nipah virus).

物理化学性质&存储条件

分子量	449.476
分子式	C24H17F2N3O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	7-((benzo[d]thiazol-2-ylamino)(4-(difluoromethoxy)phenyl)methyl)quinolin-8-ol

参考文献

1. Pattabhi S, et al. J Virol. 2015 Dec 16;90(5):2372-87.

KIN1400 (KIN-1400, KIN 1400)

生物&药学活性

物理化学性质&存储条件

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KIN1400 (KIN-1400, KIN 1400)

生物&药学活性

物理化学性质&存储条件

参考文献

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