KIF18A inhibitor compound 3

Chemical Structure : KIF18A inhibitor compound 3

加入收藏

货号: PC-22245Not For Human Use, Lab Use Only.

KIF18A inhibitor compound 3 is a potent, selective mitotic kinesin KIF18A inhibitor of IC50 of 8.2 nM, inhibits KIF18A's microtubule-stimulated ATPase activity.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

KIF18A inhibitor compound 3 is a potent, selective mitotic kinesin KIF18A inhibitor of IC50 of 8.2 nM, inhibits KIF18A's microtubule-stimulated ATPase activity.

物理化学性质&存储条件

分子量	565.64
分子式	C25H33F2N7O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-(4,4-difluoropiperidin-1-yl)-6-methylpyrimidin-4-yl)-6-((2-hydroxyethyl)sulfonamido)-4-(6-azaspiro[2.5]octan-6-yl)nicotinamide

参考文献

1. Schutt KL, et al. Front Mol Biosci. 2024 Feb 12;11:1328077.

2. Tamayo N. A., et al. J. Med. Chem. 65, 4972–4990.