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首页-小分子抑制剂&激动剂-Others-Other Targets-KG-296
KG-296

Chemical Structure : KG-296

CAS No.: 92487-46-2

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KG-296 (KG296)

货号: PC-26823Not For Human Use, Lab Use Only.

KG-296 is a small molecule ligand that bind to the PAS-A domain of NPAS2 and its paralog CLOCK, binds to CLOCK PAS-A with Kd of 120 uM, specifically binds to CLOCK/NPAS2 PAS-A domains, inhibits DNA binding to CLOCK:BMAL1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

KG-296 is a small molecule ligand that bind to the PAS-A domain of NPAS2 and its paralog CLOCK, binds to CLOCK PAS-A with Kd of 120 uM, specifically binds to CLOCK/NPAS2 PAS-A domains, inhibits DNA binding to CLOCK:BMAL1.

物理化学性质&存储条件

分子量 202.21
分子式 C12H10O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(furan-2-ylmethyl)benzoic acid

参考文献

1. Sharma D, et al. bioRxiv [Preprint]. 2026 Apr 14:2026.04.13.718289.

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