KDS2010 (Tisolagiline) | MAO-B inhibitor | Probechem Biochemicals

Chemical Structure : KDS2010

CAS No.: 1894207-44-3

加入收藏

KDS2010 (KDS-2010, Tisolagiline)

货号: PC-36146Not For Human Use, Lab Use Only.

KDS2010 (KDS-2010, Tisolagiline) is a potent, highly selective, reversible Monoamine oxidase-B (MAO-B) inhibitor with IC50 of 7.6 nM.

规格	价格	库存
10 mg	￥1480	In stock
25 mg	￥2580	In stock
50 mg	￥4280	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

KDS2010 (KDS-2010, Tisolagiline) is a potent, highly selective, reversible Monoamine oxidase-B (MAO-B) inhibitor with IC50 of 7.6 nM.
KDS2010 displays 12,500-fold selectivity over MAO-A.
KDS2010 shows a marked enantiomer selectivity (eightfold selectivity) over the (R)-isomer.
KDS2010 significantly ameliorates the impairments in spike probability, learning, and memory in APP/PS1 mice, but not by selegiline, also reverses spatial learning and memory impairments in the Morris water maze test.

物理化学性质&存储条件

分子量	322.331
分子式	C17H17F3N2O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-(((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)amino)propanamide

参考文献

1. Park JH, et al. Sci Adv. 2019 Mar 20;5(3):eaav0316. doi: 10.1126/sciadv.aav0316.

KDS2010 (KDS-2010, Tisolagiline)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

KDS2010 (KDS-2010, Tisolagiline)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.