KDM4/5 inhibitor 19a

Chemical Structure : KDM4/5 inhibitor 19a

加入收藏

货号: PC-22360Not For Human Use, Lab Use Only.

KDM4/5 inhibitor 19a is a potent, cell penetrant, dual KDM4/5-subfamily inhibitor with Ki values of 4 nM/7 nM for KDM4A/KDM5B, respectively.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

KDM4/5 inhibitor 19a is a potent, cell penetrant, dual KDM4/5-subfamily inhibitor with Ki values of 4 nM/7 nM for KDM4A/KDM5B, respectively.
KDM4/5 inhibitor 19a potently inhibits KDM4A, KDM4B, KDM5B and KDM5C with IC50 of 0.1, 0.043, 0.038 and 0.123 uM, respectively.

物理化学性质&存储条件

分子量	426.52
分子式	C25H26N6O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	8-(4-(2-(2,3-dihydrospiro[indene-1,4'-piperidin]-1'-yl)ethyl)-1H-pyrazol-1-yl)pyrido[3,4-d]pyrimidin-4(3H)-one

参考文献

1. Yann-Vaï Le Bihan, et al. Eur J Med Chem. 2019 Sep 1:177:316-337.