KCO237 | SARS-CoV-2 Nsp15 inhibitor | Probechem Biochemicals

Chemical Structure : KCO237

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KCO237 (KCO-237)

货号: PC-24849Not For Human Use, Lab Use Only.

KCO237 is a potent, reversible, non-covalent inhibitor of SARS-CoV-2 Nsp15 endoribonuclease with IC50 of 304 nM, inhibits VERO 6 cell infection with SARS-CoV-2.

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生物&药学活性

KCO237 is a potent, reversible, non-covalent inhibitor of SARS-CoV-2 Nsp15 endoribonuclease with IC50 of 304 nM, inhibits VERO 6 cell infection with SARS-CoV-2.

物理化学性质&存储条件

分子量	298.38
分子式	C15H10N2OS2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-5-((E)-3-(quinolin-4-yl)allylidene)-2-thioxothiazolidin-4-one

参考文献

1. Nimer Mehyar, et al. J Biol Chem. 2025 Jun 23:110409.

KCO237 (KCO-237)

生物&药学活性

物理化学性质&存储条件

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KCO237 (KCO-237)

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