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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phospholipase-KC01
KC01

Chemical Structure : KC01

CAS No.: 1646795-59-6

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KC01 (ABHD16A inhibitor KC01)

货号: PC-62262Not For Human Use, Lab Use Only.

KC01 is a potent and selective inhibitor of ABHD16A with IC50 of 90 nM for hABHD16A, 520 nM for mABHD16A.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    KC01 is a potent and selective inhibitor of ABHD16A with IC50 of 90 nM for hABHD16A, 520 nM for mABHD16A.
    KC01 shows significant reductions in all detected cellular lyso-PSs, no activity in other lipids, including PSs, PCs, PEs, lyso-PCs, lyso-PEs, or monoacylglycerols (MAGs).
    KC01 decreases both lyso-PSs and lipopolysaccharide-induced cytokine production in mouse macrophages.

    物理化学性质&存储条件

    分子量 365.558
    分子式 C22H39NO3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (Z)-6-(2-oxo-4-tridecyloxetan-3-ylidene)hexanamide

    参考文献

    1. Kamat SS, et al. Nat Chem Biol. 2015 Feb;11(2):164-71.

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