KBP-5074 |CAS:1359969-26-8 Probechem Biochemicals

Chemical Structure : KBP-5074

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KBP-5074 (KBP5074, Ocedurenone)

货号: PC-35939Not For Human Use, Lab Use Only.

KBP-5074 (KBP5074, Ocedurenone) is a novel non-steroidal, highly selective mineralocorticoid receptor antagonist for the treatment of hypertensive chronic kidney disease.

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生物&药学活性

KBP-5074 (KBP5074, Ocedurenone) is a novel non-steroidal, highly selective mineralocorticoid receptor antagonist for the treatment of hypertensive chronic kidney disease.

物理化学性质&存储条件

分子量	504.031
分子式	C28H30ClN5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-chloro-4-((3R,3aR)-3-cyclopentyl-7-(4-hydroxypiperidine-1-carbonyl)-3,3a,4,5-tetrahydro-2H-pyrazolo[3,4-f]quinolin-2-yl)benzonitrile

参考文献

1. Granberg K, et al. J Med Chem. 2018 Dec 31. doi: 10.1021/acs.jmedchem.8b01523.

KBP-5074 (KBP5074, Ocedurenone)

生物&药学活性

物理化学性质&存储条件

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KBP-5074 (KBP5074, Ocedurenone)

生物&药学活性

物理化学性质&存储条件

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