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首页-小分子抑制剂&激动剂-Others-Other Targets-KAN0438241
KAN0438241

Chemical Structure : KAN0438241

CAS No.: 1444836-18-3

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KAN0438241 (KAN 0438241, KAN-0438241)

货号: PC-35685Not For Human Use, Lab Use Only.

KAN0438241 (KAN-0438241) is a potent, selective PFKFB3 inhibitor with IC50 of 0.19 uM, 20-fold selectivity over PFKFB4 and no significant inhibition on PFKFB1 and 2.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    KAN0438241 (KAN-0438241) is a potent, selective PFKFB3 inhibitor with IC50 of 0.19 uM, 20-fold selectivity over PFKFB4 and no significant inhibition on PFKFB1 and 2.

    物理化学性质&存储条件

    分子量 403.38
    分子式 C19H14FNO6S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    4-((5'-fluoro-2'-hydroxy-[1,1'-biphenyl])-3-sulfonamido)-2-hydroxybenzoic acid

    参考文献

    1. Gustafsson NMS, et al. Nat Commun. 2018 Sep 24;9(1):3872.

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