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首页-小分子抑制剂&激动剂-Others-Other Targets-K784-8160
K784-8160

Chemical Structure : K784-8160

CAS No.: 474813-51-9

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K784-8160 (ZINC000006756082)

货号: PC-22325Not For Human Use, Lab Use Only.

K784-8160 is a small molecule inhibitor of tumor necrosis factor-α-induced protein 8-like 3 (TNFAIP8L3, TIPE3), exhibits potent anti-tumor activities.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

K784-8160 is a small molecule inhibitor of tumor necrosis factor-α-induced protein 8-like 3 (TNFAIP8L3, TIPE3), exhibits potent anti-tumor activities.
K784-8160 induces a dose-dependent decrease in the viability of HT-29 cells and LoVo cells, with IC50 values of 4.94 μM and 26.35 μM, respectively.

物理化学性质&存储条件

分子量 400.50
分子式 C23H20N4OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(Z)-2-(1-benzyl-2-oxoindolin-3-ylidene)-N-(o-tolyl)hydrazine-1-carbothioamide

参考文献

1. Chen X, et al. Cells. 2024 Apr 30;13(9):771.

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