K6PC-5

Chemical Structure : K6PC-5

CAS No.: 756875-51-1

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货号: PC-49431Not For Human Use, Lab Use Only.

K6PC-5 is a synthetic ceramide derivative, selective and direct sphingosine kinase 1 (SphK1) activator.

规格	价格	库存
5 mg	￥880	In stock
10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

K6PC-5 is a synthetic ceramide derivative, selective and direct sphingosine kinase 1 (SphK1) activator.
K6PC-5 ameliorates intestinal homeostasis in an animal model of Huntington's disease.
K6PC-5 increases intracellular calcium levels and promote epidermal keratinocyte differentiation, stimulates the phosphorylation of p42/44 extracellular signal-regulated kinase and c-Jun N-terminal kinase.
K6PC-5 inhibits OGD/reoxygenation-induced myocardial cell death probably through activating SphK1.
K6PC-5 markedly reduces the EBOV titer in infected cells and the de novo production of viral proteins in endothelial cells.

物理化学性质&存储条件

分子量	343.50
分子式	C19H37NO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Hexyl-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-3-oxodecanamide

参考文献

1. Kwon YB, et al. J Lipid Res. 2007 Sep;48(9):1936-43.

2. Park HY, et al. Exp Dermatol. 2008 Oct;17(10):829-36.

3. Hong JH, et al. J Invest Dermatol. 2008 Sep;128(9):2166-78.

4. Imre G, et al. iScience. 2021 Mar 5;24(4):102266.

K6PC-5

生物&药学活性

物理化学性质&存储条件

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K6PC-5

生物&药学活性

物理化学性质&存储条件

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