K67 | p62-Keap1 inhibitor | Probechem Biochemicals

Chemical Structure : K67

CAS No.: 2046250-48-8

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K67 (p-p62-Keap1 inhibitor K67)

货号: PC-62796Not For Human Use, Lab Use Only.

K67 is a specific inhibitor of the interaction between S349-phosphorylated p62 and Keap1, exhibts no inhibitory effect on the interaction of full-length Keap1 with Nrf2-ETGE or full-length Nrf2.

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10 mg	￥1980	In stock
25 mg	￥3280	In stock
50 mg	￥5280	In stock
100 mg		Get quote

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生物&药学活性

K67 is a specific inhibitor of the interaction between S349-phosphorylated p62 and Keap1, exhibts no inhibitory effect on the interaction of full-length Keap1 with Nrf2-ETGE or full-length Nrf2.
K67 has specific inhibitory effect on the Nrf2 target genes.
K67 dramatically suppresses the proliferations of Huh1 cells and of Huh7 cells expressing phospho-mimetic p62.

物理化学性质&存储条件

分子量	582.686
分子式	C29H30N2O7S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[2-acetonyl-4-(4-ethoxybenzenesulfonylamino)naphthalene-1-yl]-4-ethoxybenzenesulfonamide

参考文献

1. Saito T, et al. Nat Commun. 2016 Jun 27;7:12030.

K67 (p-p62-Keap1 inhibitor K67)

生物&药学活性

物理化学性质&存储条件

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K67 (p-p62-Keap1 inhibitor K67)

生物&药学活性

物理化学性质&存储条件

参考文献

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