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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Cdc2-like Kinase (CLK)-K00546
K00546

Chemical Structure : K00546

CAS No.: 443798-47-8

K00546 (K 00546)

货号: PC-63265Not For Human Use, Lab Use Only.

K00546 is a potent inhibitor of the CDC2-like kinase CLK1 and CLK3 with IC50 of 8.9 and 29.2 nM, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

K00546 is a potent inhibitor of the CDC2-like kinase CLK1 and CLK3 with IC50 of 8.9 and 29.2 nM, respectively.

物理化学性质&存储条件

分子量 425.433
分子式 C15H13F2N7O2S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-amino-N-(2,6-difluorophenyl)-3-((4-sulfamoylphenyl)amino)-1H-1,2,4-triazole-1-carbothioamide

参考文献

1. Fedorov O, et al. Chem Biol. 2011 Jan 28;18(1):67-76.

2. Prak K, et al. Biochemistry. 2016 Jan 26;55(3):608-17.

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