Chemical Structure : Juglone
CAS No.: 481-39-0
货号: PC-61683Not For Human Use, Lab Use Only.
Juglone (5-HN) is a plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥880 | In stock | |
50 mg | ¥1280 | In stock | |
100 mg | ¥1980 | In stock | |
250 mg | Get quote |
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Juglone (5-HN) is a plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.
Juglone inhibits the S. aureus bacterial tricarboxylic acid cycle (TCA cycle), as well as DNA and RNA synthesis, thus leading to cell collapse.
Juglone induces apoptosis of tumor stem-like cells through ROS-p38 pathway in glioblastoma in vitro and in vivo.
Juglone also reactivates latent HIV-1 through ROS and NF-kappaB without inducing global T cell activation.
分子量 | 174.16 | |
分子式 | C10H6O3 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
5-hydroxynaphthalene-1,4-dione |
1. Wang J, et al. Nat Prod Commun. 2016 Jun;11(6):825-7.
2. Yang HC, et al. J Clin Invest. 2009 Nov;119(11):3473-86.
3. Wu J, et al. BMC Neurol. 2017 Apr 7;17(1):70.
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