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首页-小分子抑制剂&激动剂-Others-Other Targets-JYQ-164
JYQ-164

Chemical Structure : JYQ-164

CAS No.:

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JYQ-164 (JYQ164)

货号: PC-22305Not For Human Use, Lab Use Only.

JYQ-164 (JYQ164) is a potent, highly selective Parkinson disease protein 7 (PARK7/DJ-1) inhibitor with IC50 of 21 nM, binds covalently and selectively to PARK7 Cys106.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

JYQ-164 (JYQ164) is a potent, highly selective Parkinson disease protein 7 (PARK7/DJ-1) inhibitor with IC50 of 21 nM, binds covalently and selectively to PARK7 Cys106.

物理化学性质&存储条件

分子量 530.62
分子式 C23H26N6O5S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-1-Cyano-N-(5-(3-(morpholinosulfonyl)benzoyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)pyrrolidine-3-carboxamide

参考文献

1. Jia Y, et al. J Med Chem. 2024 May 7. doi: 10.1021/acs.jmedchem.3c02410.

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