JX24120 | MAT2B inhibitor | Probechem Biochemicals

Chemical Structure : JX24120

加入收藏

JX24120 (JX-24120)

货号: PC-26307Not For Human Use, Lab Use Only.

JX24120 is a specific inhibitor for methionine adenosyltransferase MAT2B, directly binds to MAT2B with SPR KD of 4.72 uM, inhibits S-adenosylmethionine (SAMe) synthesis.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

JX24120 is a specific inhibitor for methionine adenosyltransferase MAT2B, directly binds to MAT2B with SPR KD of 4.72 uM, inhibits S-adenosylmethionine (SAMe) synthesis.
JX24120 induced a dose-dependent inhibition on cell viability of endometrial cancer specimens (ECOs) with IC50 of 3-7 uM.
JX24120 (5 mg/kg) induced significant tumor suppression in mice.
JX24120 inhibits energy metabolism and protein synthesis.
JX24120 induces apoptosis in endometrial cancer.

物理化学性质&存储条件

分子量	466.69
分子式	C27H38N4OS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	8-methoxy-10-(5-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pentyl)-10H-benzo[b]pyrido[2,3-e][1,4]thiazine

参考文献

1. Chunxue Zhang, et al. Pharmacol Res. 2024 Nov:209:107420.

JX24120 (JX-24120)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

JX24120 (JX-24120)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.