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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Monoamine Transporter-JX225
JX225

Chemical Structure : JX225

CAS No.: 424816-38-6

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JX225 (JX-225)

货号: PC-27192Not For Human Use, Lab Use Only.

JX225 is a potent, high-affinity inhibitor of neutral amino acid transporter B0AT1 (SLC6A19) with IC50 of 0.07 uM in FLIPR assays, and 0.44 uM in radioactive L-leucine uptake assays.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

JX225 is a potent, high-affinity inhibitor of neutral amino acid transporter B0AT1 (SLC6A19) with IC50 of 0.07 uM in FLIPR assays, and 0.44 uM in radioactive L-leucine uptake assays.

物理化学性质&存储条件

分子量 286.17
分子式 C12H16BrNO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(4-bromo-3-methylphenoxy)-N-propylacetamide

参考文献

1. Xu J, et al. Nat Commun. 2024 Aug 22;15(1):7224.

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