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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Complement System-JPE1375
JPE1375

Chemical Structure : JPE1375

CAS No.: 912344-10-6

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JPE1375 (JPE-1375, Hoo-Phe-Orn-Pro-hle-Pff-Phe-NH2)

货号: PC-72001Not For Human Use, Lab Use Only.

JPE1375 is a potent, peptidomimetic C5a receptor antagonist with IC50 of 39 nM, inhibits neutrophil influx in the RPAR in mice.

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5 mg ￥4980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

JPE1375 is a potent, peptidomimetic C5a receptor antagonist with IC50 of 39 nM.
JPE1375 inhibits neutrophil influx in the RPAR in mice.

物理化学性质&存储条件

分子量 955.102
分子式 C49H63FN10O9
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Hoo-Phe-Orn-Pro-hle-Pf-Phe-NH2

参考文献

1. Schnatbaum K, et al. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5088-92.

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