JNJ525 |CAS:2092913-64-7 Probechem Biochemicals

Chemical Structure : JNJ525

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JNJ525 (JNJ 525)

货号: PC-62163Not For Human Use, Lab Use Only.

JNJ525 is a small molecule inhibitor of TNFα that prevents the formation of TNFα complexes with TNFR1 and TNFR2 with IC50 of 1.2 uM and 1.1 uM in the TR-FRET assay, respectively.

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1 g		Get quote

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JNJ525 is a small molecule inhibitor of TNFα that prevents the formation of TNFα complexes with TNFR1 and TNFR2 with IC50 of 1.2 uM and 1.1 uM in the TR-FRET assay, respectively.

物理化学性质&存储条件

分子量	514.637
分子式	C31H30N8
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N4-benzyl-N4-(3'-(2-(piperazin-1-yl)pyrimidin-5-yl)-[1,1'-biphenyl]-2-yl)pyrimidine-2,4-diamine

参考文献

1. Blevitt JM, et al. J Med Chem. 2017 Apr 27;60(8):3511-3517.

JNJ525 (JNJ 525)

生物&药学活性

物理化学性质&存储条件

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JNJ525 (JNJ 525)

生物&药学活性

物理化学性质&存储条件

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