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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-PPAR-JNJ 39659100
JNJ 39659100

Chemical Structure : JNJ 39659100

CAS No.: 24136-23-0

JNJ 39659100 (MBX-102, Arhalofenate)

货号: PC-49252Not For Human Use, Lab Use Only.

JNJ39659100 (MBX-102) is a nonthiazolidinedione (TZD) selective partial PPAR-γ agonist with insulin-sensitizing and glucose-lowering properties comparable to TZDs without dose-dependent increases in body weight, the prodrug ester of MBX-102 acid.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

JNJ 39659100 (Arhalofenate, MBX-102) is a nonthiazolidinedione (TZD) selective partial PPAR-γ agonist with insulin-sensitizing and glucose-lowering properties comparable to TZDs without dose-dependent increases in body weight, the prodrug ester of MBX-102 acid.

物理化学性质&存储条件

分子量 415.793
分子式 C19H17ClF3NO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-acetamidoethyl (R)-2-(4-chlorophenyl)-2-(3-(trifluoromethyl)phenoxy)acetate

参考文献

1. Gregoire FM, et al. Mol Endocrinol. 2009 Jul;23(7):975-88.

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