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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Aminopeptidase-JNJ-4929821
JNJ-4929821

Chemical Structure : JNJ-4929821

CAS No.: 836671-12-6

JNJ-4929821 (JNJ4929821)

货号: PC-63315Not For Human Use, Lab Use Only.

JNJ-4929821 is a potent, reversible methionine aminopeptidase-2 (MetAP-2) inhibitor with IC50 of 8 nM..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    JNJ-4929821 is a potent, reversible methionine aminopeptidase-2 (MetAP-2) inhibitor with IC50 of 8 nM.

    物理化学性质&存储条件

    分子量 352.402
    分子式 C14H13FN4O2S2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-((4H-1,2,4-triazol-3-yl)methyl)-N-(4-fluorobenzyl)thiophene-2-sulfonamide

    参考文献

    1. Heinrich T, et al. Bioorg Med Chem Lett. 2017 Feb 1;27(3):551-556.

    2. Garrabrant T, et al. Angiogenesis. 2004;7(2):91-6.

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