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首页-小分子抑制剂&激动剂-GPCR-mGluR-JNJ-42491293
JNJ-42491293

Chemical Structure : JNJ-42491293

CAS No.: 1376334-37-0

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JNJ-42491293 (JNJ42491293)

货号: PC-20314Not For Human Use, Lab Use Only.

JNJ-42491293 (JNJ 42491293) is a potent, mGlu2-selective allosteric agonist and positive allosteric modulator (ago-PAM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    JNJ-42491293 (JNJ 42491293) is a potent, mGlu2-selective allosteric agonist and positive allosteric modulator (ago-PAM).

    物理化学性质&存储条件

    分子量 432.90
    分子式 C22H23ClF2N4O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    8-chloro-3-(cyclopropylmethyl)-7-(4-(3,6-difluoro-2-methoxyphenyl)piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridine

    参考文献

    1. Christian B M Poulie, et al. J Med Chem. 2020 Sep 10;63(17):9928-9949.

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