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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-TRP Channel-JNJ-38893777
JNJ-38893777

Chemical Structure : JNJ-38893777

CAS No.: 951135-00-5

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JNJ-38893777 (JNJ38893777)

货号: PC-63428Not For Human Use, Lab Use Only.

JNJ-38893777 is a potent and selective transient receptor potential vanilloid 1 (TRPV1) channel antagonist for treatment of ociceptive and neuropathic pain.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    JNJ-38893777 is a potent and selective transient receptor potential vanilloid 1 (TRPV1) channel antagonist for treatment of ociceptive and neuropathic pain.

    物理化学性质&存储条件

    分子量 536.526
    分子式 C26H26F6N6
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-(1-piperidinyl)-N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine

    参考文献

    1. Manitpisitkul P, et al. Clin Drug Investig. 2015 Jun;35(6):353-63.

    2. Meents JE, et al. J Headache Pain. 2015;16:57.

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