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首页-小分子抑制剂&激动剂-Others-Diacylglycerol Kinase (DGK)-JNJ-3790339
JNJ-3790339

Chemical Structure : JNJ-3790339

CAS No.: 93076-87-0

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JNJ-3790339 (JNJ 3790339)

货号: PC-38842Not For Human Use, Lab Use Only.

JNJ-3790339 is a potent and selective inhibitor of diacylglycerol kinase α (DGKα), demonstrates similar cytotoxicity in GBM and melanoma cells as ritanserin.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    JNJ-3790339 is a potent and selective inhibitor of diacylglycerol kinase α (DGKα), demonstrates similar cytotoxicity in GBM and melanoma cells as ritanserin.

    物理化学性质&存储条件

    分子量 483.674
    分子式 C30H33N3OS
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    6-(2-(4-(di-p-tolylmethylene)piperidin-1-yl)ethyl)-3,7-dimethyl-5H-thiazolo[3,2-a]pyrimidin-5-one

    参考文献

    1. Mitchell E Granade, et al. Biochem Pharmacol. 2022 Mar;197:114908.

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