JNJ-37822681 |CAS:935776-74-2 Probechem Biochemicals

Chemical Structure : JNJ-37822681

CAS No.: 935776-74-2

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JNJ-37822681 (JNJ37822681)

货号: PC-61553Not For Human Use, Lab Use Only.

JNJ-37822681 is a potent, specific and fast-dissociating dopamine D2 antagonist with Ki of 158 nM.

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5 mg	￥980	In stock
10 mg	￥1480	In stock
25 mg	￥2580	In stock
50 mg	￥3980	In stock
100 mg		Get quote

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生物&药学活性

JNJ-37822681 is a potent, specific and fast-dissociating dopamine D2 antagonist with Ki of 158 nM.
JNJ-37822681 shows no significant affinity for α1, α2, H1, muscarinic, and 5-HT2C receptors, D1, D3, and 5-HT2A.
JNJ-37822681 exhibits potential therapeutic value for the treatment of schizophrenia and bipolar disorder with optimal brain disposition.

物理化学性质&存储条件

分子量	372.34
分子式	C17H17F5N4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[1-[(3,4-Difluorophenyl)methyl]-4-piperidinyl]-6-(trifluoromethyl)-3-pyridazinamine

参考文献

1. Langlois X, et al. J Pharmacol Exp Ther. 2012 Jul;342(1):91-105.

2. Schmidt ME, et al. Psychopharmacology (Berl). 2012 Dec;224(4):549-57.

3. te Beek ET, et al. J Psychopharmacol. 2012 Aug;26(8):1119-27.

JNJ-37822681 (JNJ37822681)

生物&药学活性

物理化学性质&存储条件

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JNJ-37822681 (JNJ37822681)

生物&药学活性

物理化学性质&存储条件

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