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首页-小分子抑制剂&激动剂-Others-Other Targets-JNJ-1289
JNJ-1289

Chemical Structure : JNJ-1289

CAS No.: 792898-18-1

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JNJ-1289 (JNJ1289)

货号: PC-49232Not For Human Use, Lab Use Only.

JNJ-1289 (JNJ1289) is a potent, highly selective allosteric inhibitor of human spermine oxidase (hSMOX) with IC50 of 50 nM, inactive against hPAOX and LSD1 (IC50>2,000 nM).

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10 mg ￥5780 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

JNJ-1289 (JNJ1289) is a potent, highly selective allosteric inhibitor of human spermine oxidase (hSMOX) with IC50 of 50 nM, inactive against hPAOX and LSD1 (IC50>2,000 nM).

物理化学性质&存储条件

分子量 308.359
分子式 C16H12N4OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-((4-imidazo[1,2,a]pyridine-3-ylthiazol-2-yl)amino)phenol

参考文献

1. Elsie Diaz, et al. Commun Biol. 2022 Aug 5;5(1):787.

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