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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-RSV-JMN3-003
JMN3-003

Chemical Structure : JMN3-003

CAS No.: 1331868-55-3

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JMN3-003 (JMN 3-003)

货号: PC-73389Not For Human Use, Lab Use Only.

JMN3-003 is a host-directed inhibitor with potent antiviral activity against a panel of myxovirus family members with EC50 of 10-70 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    JMN3-003 is a host-directed inhibitor with potent antiviral activity against a panel of myxovirus family members with EC50 of 10-70 nM.
    JMN3-003 shows activity against MeV at 170 (viral CPE-reduction assay) and 30 nM (virus yield reduction assay) and does not display any detectable acute cytotoxicity.
    JMN3-003 also shows superb antiviral activity against a selection of clinical-relevant paramyxovirus (RSV, MuV, and HPIV3) and orthomyxovirus (influenza) family members.

    物理化学性质&存储条件

    分子量 451.969
    分子式 C24H22ClN3O2S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(2-chloro-4-methylphenyl)-2-((1-(4-methoxyphenyl)-1H-benzo[d]imidazol-2-yl)thio)propanamide

    参考文献

    1. Sun A, et al. ACS Med Chem Lett. 2011 Aug 23;2(11):798-803.

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