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首页-小分子抑制剂&激动剂-Epigenetics-Histone Demethylase-JMJD1C inhibitor 193D7
JMJD1C inhibitor 193D7

Chemical Structure : JMJD1C inhibitor 193D7

CAS No.: 861224-48-8

JMJD1C inhibitor 193D7 (193D7)

货号: PC-21777Not For Human Use, Lab Use Only.

193D7 is a specific and oral inhibitor of histone demethylase JMJD1C with IC50 of 0.59 uM in in vitro demethylation assays, suppresses tumor growth by targeting intratumoral Treg cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

193D7 is a specific and oral inhibitor of histone demethylase JMJD1C with IC50 of 0.59 uM in in vitro demethylation assays, suppresses tumor growth by targeting intratumoral Treg cells.

物理化学性质&存储条件

分子量 317.36
分子式 C16H15NO4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(8-benzoyl-5-oxo-2,3,6,7-tetrahydro-5H-thiazolo[3,2-a]pyridin-6-yl)acetic acid

参考文献

1. Long X, et al. Nat Immunol. 2024 Feb 14. doi: 10.1038/s41590-024-01746-8.

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