JLT048 | TDP1/2 inhibitor | Probechem Biochemicals

Chemical Structure : JLT048

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货号: PC-20287Not For Human Use, Lab Use Only.

JLT048 is a small molecule inhibitor of tyrosyl-DNA-phosphodiesterases 1 and 2 (TDP1 and TDP2) with IC50 of 7.7 and 32 uM, respectively.

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JLT048 is a small molecule inhibitor of tyrosyl-DNA-phosphodiesterases 1 and 2 (TDP1 and TDP2) with IC50 of 7.7 and 32 uM, respectively.

分子量	406.37
分子式	C22H15FN2O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[5-[[1-[(2-Fluorophenyl)methyl]-2,5-dioxo-4-imidazolidinylidene]methyl]-2-furanyl]benzoic acid

1. Marchand C, et al. Mol Cancer Ther. 2014 Aug;13(8):2116-26.