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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Influenza Virus-JJ3297
JJ3297

Chemical Structure : JJ3297

CAS No.: 153810-66-3

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JJ3297 (JJ 3297)

货号: PC-38714Not For Human Use, Lab Use Only.

JJ3297 is a potent antagonist of influenza virus non-structural protein 1 (NS1), strongly restores IFN-β mRNA levels and inhibits viral replication in MDCK cells (IC50=0.8 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

JJ3297 is a potent antagonist of influenza virus non-structural protein 1 (NS1), strongly restores IFN-β mRNA levels and inhibits viral replication in MDCK cells (IC50=0.8 uM).
JJ3297 inhibits influenza viral infection multi-cycle but not single-cycle infections, effectively inhibits the synthesis of IFN in infected cells.

物理化学性质&存储条件

分子量 255.317
分子式 C16H17NO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-hydroxy-N-(3-phenylpropyl)benzamide

参考文献

1. Walkiewicz MP, et al. J Gen Virol. 2011 Jan;92(Pt 1):60-70.

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