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首页-小分子抑制剂&激动剂-Immunology/Inflammation-IRAK-JH-XI-82-01
JH-XI-82-01

Chemical Structure : JH-XI-82-01

CAS No.: 2918188-22-2

JH-XI-82-01

货号: PC-28200Not For Human Use, Lab Use Only.

JH-XI-82-01 is a potent, selective dual IRAK1/IRAK4 inhibitor with enzymetic IC50 of 3 nM and 7 nM respectively.

规格 价格 库存 数量
25 mg Get quote
50 mg Get quote
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

JH-XI-82-01 is a potent, selective dual IRAK1/IRAK4 inhibitor with enzymetic IC50 of 3 nM and 7 nM respectively.

物理化学性质&存储条件

分子量 456.55
分子式 C25H28N8O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(3-(1-isopropylpiperidin-4-yl)-1-(pyridin-2-yl)-1H-pyrazol-5-yl)-6-(1H-pyrazol-5-yl)picolinamide

参考文献

1. Hatcher JM, et al. ACS Med Chem Lett. 2026 Aug 26;17(9):1977-1988.

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