欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-GPCR-Opioid Receptor-JDTic
JDTic

Chemical Structure : JDTic

CAS No.: 361444-66-8

加入收藏

JDTic

货号: PC-42614Not For Human Use, Lab Use Only.

JDTic is a highly potent and selective kappa opioid receptor (KOR) antagonist with Ki of 0.3 nM.

规格 价格 库存 数量
10 mg ￥1980 In stock
25 mg ￥3280 In stock
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

JDTic is a  highly potent and selective kappa opioid receptor (KOR) antagonist with Ki of 0.3 nM.
JDTic has a Ki of 0.006 nM in GTP-gamma-S assay, displays >15,000-fold selectivity over delta receptors.
JDTic exhibits anxiolytic-like effects in models of unlearned and learned fear in rats.

物理化学性质&存储条件

分子量 465.6276
分子式 C28H39N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-Isoquinolinecarboxamide, 1,2,3,4-tetrahydro-7-hydroxy-N-[(1S)-1-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-2-methylpropyl]-, (3R)-

参考文献

1. Thomas JB, et al. J Med Chem. 2001 Aug 16;44(17):2687-90.

2. Carroll I, et al. Eur J Pharmacol. 2004 Oct 6;501(1-3):111-9.

3. Beardsley PM, et al. Psychopharmacology (Berl). 2005 Nov;183(1):118-26.

4. Knoll AT, et al. J Pharmacol Exp Ther. 2007 Dec;323(3):838-45.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: