JC744 | p53 Y220C reactivator | Probechem Biochemicals

Chemical Structure : JC744

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货号: PC-25766Not For Human Use, Lab Use Only.

JC744 is a small molecule stabilizer and reactivator of p53 Y220C mutant with Kd of 320 nM.

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JC744 is a small molecule stabilizer and reactivator of p53 Y220C mutant with Kd of 320 nM.

分子量	475.28
分子式	C16H15FIN3O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(diethylamino)-7-(3-fluoro-1H-pyrrol-1-yl)-5-hydroxy-6-iodobenzo[d]thiazole-4-carboxylic acid

1. Stephenson Clarke JR, et al. ACS Pharmacol Transl Sci. 2022 Oct 11;5(11):1169-1180.