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JBD1

Chemical Structure : JBD1

CAS No.: 577981-37-4

JBD1 (S. aureus biofilm inhibitor)

货号: PC-49157Not For Human Use, Lab Use Only.

JBD1 is a small molecule compound that strongly inhibits biofilm formation of S. aureus, including methicillin-resistant strains, induces biofilm inhibition and metabolic remodeling through respiratory activation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    JBD1 is a small molecule compound that strongly inhibits biofilm formation of S. aureus, including methicillin-resistant strains, induces biofilm inhibition and metabolic remodeling through respiratory activation.
    JBD1 activated the respiratory activity of S. aureus cells and increased the sensitivity to aminoglycosides.
    JBD1 altered the metabolic profile of S. aureus and induced metabolic remodeling.

    物理化学性质&存储条件

    分子量 349.475
    分子式 C19H31N3O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (E)-3-cyclohexyl-5-(1-(hexylamino)propylidene)-6-hydroxypyrimidine-2,4(3H,5H)-dione

    参考文献

    1. Ken-Ichi Okuda, et al. mBio. 2022 Jul 19;e0084522.

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