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JAK-IN-21

Chemical Structure : JAK-IN-21

CAS No.: 2445499-20-5

JAK-IN-21

货号: PC-49377Not For Human Use, Lab Use Only.

JAK-IN-21 is a selective and potent JAK inhibitor with IC50 of 1.73, 2.04, 109 and 62.9 nM against JAK1, JAK2, J2V617F and TYK2, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

JAK-IN-21 is a selective and potent JAK inhibitor with IC50 of 1.73, 2.04, 109 and 62.9 nM against JAK1, JAK2, J2V617F and TYK2, respectively.

物理化学性质&存储条件

分子量 372.392
分子式 C19H16N8O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(Cyanomethyl)-4-[2-[[1-(cyanomethyl)-1H-pyrazol-4-yl]amino]-5-methyl-4-pyrimidinyl]benzamide

参考文献

1. Patent WO2020119819.

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