JAB-3068 | SHP2 inhibitor | Probechem Biochemicals

Chemical Structure : JAB-3068

CAS No.: 2169223-48-5

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货号: PC-20250Not For Human Use, Lab Use Only.

JAB-3068 (JAB3068) is a potent, selective and orally bioavailable allosteric inhibitor of SHP2 with IC50 of 25.8 nM.

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JAB-3068 (JAB3068) is a potent, selective and orally bioavailable allosteric inhibitor of SHP2 with IC50 of 25.8 nM.

分子量	476.54
分子式	C22H26F2N6O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-[4-[[3-Amino-5-[(4S)-4-amino-2-oxa-8-azaspiro[4.5]dec-8-yl]-2-pyrazinyl]thio]-3,3-difluoro-2,3-dihydro-1H-indol-1-yl]ethanone

1. Patent WO2022135346 A1.