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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-J8-C8
J8-C8

Chemical Structure : J8-C8

CAS No.: 1150565-77-7

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J8-C8 (TofI inhibitor J8-C8)

货号: PC-62035Not For Human Use, Lab Use Only.

J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production.
    J8-C8 inhibits N-octanoyl-L-HSL (C8-HSL) synthesis in a dose-dependent manner.
    J8-C8 is a new class of quorum sensing (QS)-inhibiting therapeutic agents.

    物理化学性质&存储条件

    分子量 237.343
    分子式 C14H23NO2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(3-oxocyclohex-1-en-1-yl)octanamide

    参考文献

    1. Chung J, et al. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12089-94.

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