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首页-抗体和重组蛋白-Biosimilar Antibody-Ivuxolimab
Ivuxolimab

Chemical Structure : Ivuxolimab

CAS No.:

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Ivuxolimab (Anti-human OX40 mAb, human IgG2-Kappa; PF-04518600)

货号: PC-Ab1021Not For Human Use, Lab Use Only.

PF-04518600 selectively binds to and activates OX40, activating the dormant immune response, which then may help fight cancer cells. The activation of OX40 could also suppress the activity of regulatory-T cells, further increasing the immune response against cancer cells..

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1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PF-04518600 selectively binds to and activates OX40, activating the dormant immune response, which then may help fight cancer cells. The activation of OX40 could also suppress the activity of regulatory-T cells, further increasing the immune response against cancer cells.

物理化学性质&存储条件

分子量
分子式 Human IgG2-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

PF-04518600; PF-8600;OX40; CD134; OX40L; OX40-OX40L interaction; OX40 agonist; Anti-TNFRSF4/CD134 mAb

参考文献

1. 1, Diab A, et al. Clin Cancer Res. 2021 Oct 6:clincanres.0845.2021. 2, Cebada J, et al. Expert Opin Ther Pat. 2021 Jan;31(1):81-90.

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