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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-HCN Channel-Ivabradine hydrochloride
Ivabradine hydrochloride

Chemical Structure : Ivabradine hydrochloride

CAS No.: 148849-67-6

Ivabradine hydrochloride

货号: PC-22225Not For Human Use, Lab Use Only.

Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker, inhibits the cardiac pacemaker current (If).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker, inhibits the cardiac pacemaker current (If).

物理化学性质&存储条件

分子量 505.05
分子式 C27H37ClN2O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one hydrochloride

参考文献

1. Tardif JC, et al. Eur Heart J. 2005 Dec;26(23):2529-36.

2. Du XJ, et al. Br J Pharmacol. 2004 May;142(1):107-12.

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