Istradefylline |CAS:155270-99-8 Probechem Biochemicals

Chemical Structure : Istradefylline

CAS No.: 155270-99-8

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Istradefylline (KW 6002;KW-6002;KW6002)

货号: PC-42728Not For Human Use, Lab Use Only.

Istradefylline (KW6002) is a potent and highly selective A2A receptor antagonist with Ki of 2.2 nM.

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10 mg	￥680	In stock
25 mg	￥1080	In stock
50 mg	￥1680	In stock
100 mg	￥2380	In stock
250 mg		Get quote

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生物&药学活性

Istradefylline (KW6002) is a potent and highly selective A2A receptor antagonist with Ki of 2.2 nM.
KW6002 significantly increases the total counts of turning induced by apomorphine at doses 1 mg/kg, p.o.
KW6002 also potentiates the rotational behavior induced by L-DOPA at a dose of 3 mg/kg, p.o.

物理化学性质&存储条件

分子量	384.429
分子式	C20H24N4O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: < 6 mg/mL
Chemical Name/SMILES	1H-Purine-2,6-dione, 8-[(1E)-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-3,7-dihydro-7-methyl-

参考文献

1. Koga K, et al. Eur J Pharmacol. 2000 Nov 24;408(3):249-55.

2. Chen JF, et al. J Neurosci. 2001 May 15;21(10):RC143.

3. Ochi M, et al. Neuroscience. 2000;100(1):53-62.

Istradefylline (KW 6002;KW-6002;KW6002)

生物&药学活性

物理化学性质&存储条件

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Istradefylline (KW 6002;KW-6002;KW6002)

生物&药学活性

物理化学性质&存储条件

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