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首页-小分子抑制剂&激动剂-NF-κB Pathway-NF-κB-Isoquercetin
Isoquercetin

Chemical Structure : Isoquercetin

CAS No.: 482-35-9

Isoquercetin (3-Glucosylquercetin)

货号: PC-62114Not For Human Use, Lab Use Only.

Isoquercetin is a flavonoid and 3-O-glucoside of quercetin that displays selective cytotoxicity to cancer cells, primarily by inducing apoptosis and cell cycle arrest, regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system.

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25 mg ¥980 In stock
50 mg ¥1480 In stock
100 mg ¥2380 In stock
250 mg ¥3980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Isoquercetin is a flavonoid and 3-O-glucoside of quercetin that displays selective cytotoxicity to cancer cells, primarily by inducing apoptosis and cell cycle arrest, regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system.

物理化学性质&存储条件

分子量 464.379
分子式 C21H20O12
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-[(3R,4R,5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxy-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one

参考文献

1. Huang XL, et al. Oncotarget. 2017 Sep 16;8(60):101545-101559.

2. Chen F, et al. Oncol Rep. 2016 Jul;36(1):165-72.

3. Zhu M, et al. Molecules. 2016 Mar 21;21(3):356.

4. Wu P, et al. Food Funct. 2017 Oct 18;8(10):3707-3722.

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