Isopomiferin

Chemical Structure : Isopomiferin

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货号: PC-21524Not For Human Use, Lab Use Only.

Isopomiferin is a prenylated isoflavonoid, collapses the tumor checkpoint module (TCM) and suppresses both MYCN and TEAD4 in MYCN-amplified NBL cells.

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生物&药学活性

Isopomiferin is a prenylated isoflavonoid, collapses the tumor checkpoint module (TCM) and suppresses both MYCN and TEAD4 in MYCN-amplified NBL cells.
Isopomiferin inhibited casein kinase 2 (CK2) in cells.
Isopomiferin inhibited MYC and MYCN in NBL and lung cancer cells.

物理化学性质&存储条件

分子量	420.46
分子式	C25H24O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	11-(3,4-dihydroxyphenyl)-2,2,6,6-tetramethyl-3,4-dihydro-2H,6H,12H-dipyrano[2,3-f:2',3'-h]chromen-12-one

参考文献

1. Stokes ME, et al. Cell Chem Biol. 2023 Dec 6:S2451-9456(23)00422-1.

2. Robles S, et al. Curr Drug Discov Technol. 2017;14(3):156-168.

Isopomiferin

生物&药学活性

物理化学性质&存储条件

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Isopomiferin

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物理化学性质&存储条件

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