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首页-小分子抑制剂&激动剂-Epigenetics-Bromodomain-Ischemin sodium
Ischemin sodium

Chemical Structure : Ischemin sodium

CAS No.: N/A

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Ischemin sodium

货号: PC-60198Not For Human Use, Lab Use Only.

Ischemin sodium is a cell permeable CBP bromodomain inhibitor with Kd of 19 uM.

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5 mg ￥1980 In stock
10 mg ￥2980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ischemin sodium is a cell permeable CBP bromodomain inhibitor with Kd of 19 uM.
Ischemin sodium inhibits the acetyl-lysine binding activity of CBP, inhibits p53 interaction with CBP and decreases p53 transcriptional activity.
Ischemin sodium protects against doxorubicin-induced apoptosis in cardiomyocytes in vitro.

物理化学性质&存储条件

分子量 357.36
分子式 C15H16N3O4SNa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-2,4-dimethylbenzenesulfonic acid sodium salt

参考文献

1. Borah JC, et al. Chem Biol. 2011 Apr 22;18(4):531-41.

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