Chemical Structure : Ischemin
货号: PC-60199Not For Human Use, Lab Use Only.
Ischemin is a cell permeable CBP bromodomain inhibitor with Kd of 19 uM.
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Ischemin is a cell permeable CBP bromodomain inhibitor with Kd of 19 uM.
Ischemin inhibits the acetyl-lysine binding activity of CBP, inhibits p53 interaction with CBP and decreases p53 transcriptional activity.
Ischemin protects against doxorubicin-induced apoptosis in cardiomyocytes in vitro.
分子量 | 335.378 | |
分子式 | C15H17N3O4S | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Borah JC, et al. Chem Biol. 2011 Apr 22;18(4):531-41.
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