Irsenontrine (E2027)

Chemical Structure : Irsenontrine

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货号: PC-38401Not For Human Use, Lab Use Only.

Irsenontrine (E2027) is a potent, selective and orally active phosphodiesterase 9 (PDE9) inhibitor, reduces the degradation of cyclic GMP (cGMP) which is critical to signal transmission among cells, and helps maintain the concentration of cGMP in the brain.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Irsenontrine (E2027) is a potent, selective and orally active phosphodiesterase 9 (PDE9) inhibitor, reduces the degradation of cyclic GMP (cGMP) which is critical to signal transmission among cells, and helps maintain the concentration of cGMP in the brain.

物理化学性质&存储条件

分子量	390.443
分子式	C22H22N4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-7-(2-methoxy-3,5-dimethylpyridin-4-yl)-1-(tetrahydrofuran-3-yl)-1,5-dihydro-4H-pyrazolo[4,3-c]quinolin-4-one

参考文献

1. Patent WO2018221550 A1