Irosustat |CAS:288628-05-7 Probechem Biochemicals

Chemical Structure : Irosustat

CAS No.: 288628-05-7

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Irosustat (STX-64;BN-83495;Oristusane;667-coumate)

货号: PC-61431Not For Human Use, Lab Use Only.

Irosustat (STX-64, BN-83495, Oristusane, 667-coumate) is an orally active, highly potent, irreversible, nonsteroidal inhibitor of steroid sulfatase (STS) with IC50 of 8 nM.

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50 mg	￥4280	In stock
100 mg	￥7280	In stock
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生物&药学活性

Irosustat (STX-64, BN-83495, Oristusane, 667-coumate) is an orally active, highly potent, irreversible, nonsteroidal inhibitor of steroid sulfatase (STS) with IC50 of 8 nM; inhibits the production of locally active estrogens and so inhibit estrogen-dependent cell growth in tumor cells; inhibits estrone sulfate-stimulated growth of uteri in ovariectomized rats.

物理化学性质&存储条件

分子量	309.336
分子式	C14H15NO5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Sulfamic acid, 6,7,8,9,10,11-hexahydro-6-oxobenzo[b]cyclohepta[d]pyran-3-yl ester

参考文献

1. Purohit A, et al. Cancer Res. 2000 Jul 1;60(13):3394-6.

2. Woo LL, et al. Chem Biol. 2000 Oct;7(10):773-91.

3. Stanway SJ, et al. Clin Cancer Res. 2006 Mar 1;12(5):1585-92.

Irosustat (STX-64;BN-83495;Oristusane;667-coumate)

生物&药学活性

物理化学性质&存储条件

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Irosustat (STX-64;BN-83495;Oristusane;667-coumate)

生物&药学活性

物理化学性质&存储条件

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