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首页-小分子抑制剂&激动剂-Others-Other Targets-Iopanoic acid
Iopanoic acid

Chemical Structure : Iopanoic acid

CAS No.: 96-83-3

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Iopanoic acid

货号: PC-28614Not For Human Use, Lab Use Only.

Iopanoic acid (IOP) is a potent inhibitor of type I and type II 5'-deiodinase (DIO1 and DIO2), produces rapid, reversible suppression of peripheral thyroxine (T4) to T3 conversion, alongside comparative rescue strategies including Lugol's iodine, perchlorate, lithium, cholestyramine.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Iopanoic acid (IOP) is a potent inhibitor of type I and type II 5'-deiodinase (DIO1 and DIO2), produces rapid, reversible suppression of peripheral thyroxine (T4) to T3 conversion, alongside comparative rescue strategies including Lugol's iodine, perchlorate, lithium, cholestyramine.

物理化学性质&存储条件

分子量 570.94
分子式 C11H12I3NO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(3-Amino-2,4,6-triiodobenzyl)butanoic acid

参考文献

1. Renko K, et al. Thyroid. 2015 Aug;25(8):962-8.

2. Taylor P, et al. J Clin Endocrinol Metab. 2026 Oct 14:dgag421.

3. Newman C, et al. Eur Thyroid J. 2026 Mar 18;15(2):ETJ250350.

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